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SANTAROS KLINIKOS

VILNIAUS UNIVERSITETO LIGONINĖ

Scientific activity

Spausdinti

ARTICLES in the journals included in Master Journal List of Institute of Scientific Information (ISI) (with full journal name as indicated in ISI Master Journal List). Centre of Hepatology, Gastroenterology and Dietetics.

  1. Valantinas J., Liakina V., Speiciene D., Irnius A., Semuchiniene T., Association of the prevalence and grade of steatosis in patients with chronic hepatitis C with the host and viral factors. Acta Gastroenterologica Belgica 2007; 70:260-266.
  2. Irnius A., Speiciene D., Tautkus S., Kareiva A. Distribution of sodium, potassium, magnesium and calcium in blood plasma. Mendeleev Communications 2007;17:216-217.
  3. Tautkus S., Irnius A., Speiciene D., Barkauskas J., Kareiva A. Investigation of distribution of heavy metals between blood plasma and blood cells. Annali di chimica 2007; 97(11-12):1139-1142.
  4. Speiciene D., Irnius A., Leuschner U., Liakina V., Semuchiniene T., Barakauskiene A. Primary biliary cirrhosis in Lithuania: diagnosis and clinical picture. Medical Science Monitor 2007; 13(7):299-306.
  5. Liakina V., Speiciene D., Irnius A., Valantinas J. Changes in hepatitis C virus infection routes and genotype distribution in a Lithuanian cohort with chronic hepatitis C. Medical Science Monitor 2009;15(4):PH17-23.
  6. Paskonis M., Masalaite L., Buivydiene A., Sokolovas V., Jurgaitis J., Jurevicius S., Mikalauskas S., Gutauskas M., Spuras J., Sarkaite R., Samuilis A., Rutkauskaite D., Misionis N., Dukstaite A., Serpytis M., Kekstas G., Rainiene T., Barakauskiene A., Valantinas J., Strupas K. Orthotopic liver transplantation: The first experience and results of the Vilnius University Hospital Santariskių Klinikos. Annals of2010;15:14-24.
  7. Ausrine Baranauskiene, Danute Speiciene, Valentina Liakina, Terese Semuchiniene, Jonas Valantinas. Expression of Cytokeratin 7 as a Histological Marker of Cholestasis ant Stages of Primary Biliary Cirrhosis. Medicina 2011;47(1):31-8.
  8. Valentina Liakina, Valantinas Jonas. Anti-HCV prevalence in the general population of Lithuania. Medical science2012, vol. 18, no. 3.  ISSN 1234-1010 p. PH28-35.
  9. Valentina Liakina, Arida Buivydienė, Ilona Savlan, Diana Aksionova. Lėtiniu vurusiniu C hepatitu sergančių ligonių neinvazinis kepenų fibrozės vertinimas. Laboratorinė2012, t. 14, nr. 1.  ISSN 1392-6470 p. 3-7.
  10. Jonas Valantinas, Laura Mašalaitė, Juozas Stanaitis. Recurrence of esophageal varices after endoscopic band ligation. Acta medica2012, vol. 19, nr. 2.  ISSN 1392-0138 p. 59-66.
  11. Valentina Liakina, Tomas Abalikšta, Kęstutis Strupas, Gintautas Brimas. Metabolic changes one year after laparoscopic adjustable gastric banding operation in morbidly obese subjects. Videosurgery and other miniinvasiveISSN 1895-4588 2013, Vol. 8, no. 1. p. 13-21.
  12. Jonas Valantinas, Ilona Savlan, Valentinas Liakina. Diagnosis and treatment of hepatic encephalopathy. Acta medica2013, vol. 20, nr. 1.  ISSN 1392-0138 p. 1-11.
  13. Jonas Valantinas, Ilona Savlan, Valentinas Liakina. Value of computerized inhibitory control test and blood tests in minimal hepatic encephalopathy diagnosis. Acta medica2013, vol. 20, nr. 3.  ISSN 1392-0138 p. 109-116.
  14. Jonas Valantinas, Laura Mašalaitė, Juozas Stanaitis. Esophageal collateral veins as predictors for variceal recurrence following endoscopic band ligation. European journal of gastroenterology and2013, vol. 28, suppl. 3.  ISSN 0815-9319 p. 620.
  15. Jonas Valantinas, Laura Mašalaitė, Juozas Stanaitis. The role of collateral veins detected by endosonography in predicting the recurrence of esophageal varices after endoscopic treatment: a systematic review. HepatologyISSN 1936-0533 2014, vol. 8, no 3. p. 339-351.
  16. Jonas Valantinas, Valentina Liakina, Ilona Savlan. Concise review of current concepts on nomenclature and pathophysiology of hepatic encephalopathy.2014, t. 50, nr. 1.  ISSN 1010-660X p. 75-81.

Performed and ongoing research projects:

1. ”Family Study in Primary Biliary Cirrhosis” - international research project for the study of genetic markers of primary biliary cirrhosis. Project start and end dates: 2008-2012. Coordinator: Toronto University Western Hospital (prof. J. Heathcote). 23 participants from North America and Europe. Project manager in Lithuania prof. J. Valantinas).

2. ”Chronic liver diseases pathogenetic links with the other abdominal organs disorders and optimization of consevative and surgical treatment” – research project supported by state budget. Project start and end dates: 2008 – 2011. Project manager prof. J. Valantinas. The project purpose is to evaluate immune responce and histological charcteristics of patients with chronic liver diseases; to assess the liver disease influence on patient’s cognitive functions; to optimize treatment srategy and tactics.

2011 year aim: to detect anti-HCV prevalence in the general population and ascertain risk factors for HCV infection in the population. To evaluate the effectiveness of HCV spread preventive methods.

To evaluate a prevalence of minimal hepatic encephalopathy in patients with vaious etiology liver cirrhosis.

3. ”Anti-HCV prevalence in the general population” – research project for the study of HCV epidemiology. Project start and end dates: from 2010. The project was odered by JSC ROCHE LIETUVA. Project coordinator: dr. V. Liakina

4. “Prevalence of HCV, HBV and H. pylori infections markers among high school students of various regions of Lithuania” – epidemiological research project. Project start and end dates: 2008. The research project was supported by Lithuanian Science and Study Foundation. Project manager dr. V. Liakina.

5. “Search for the new serological markers for prognosis of treatment response in patients with chronic hepatitis C” – research project for the study of changes in peripheral blood Th1 and Th2 citokines ratio in patients with chronic hepatitis C before and during antiviral treatment. Project start and end dates: 2006. Project was supported by Lithuanian Science and Study Foundation. Project manager dr. V. Liakina.

Research interests:

Research of liver and pancreas transplantation techniques;
Risk factors for acquisition of HCV infection;
Autoimmune presentation of chronic hepatitis C;
Differences in immune response of chronic hepatitis C patients and prognosis of treatment failure;
Improvement of diagnostic tools and search for new treatment possibilities of viral hepatitis C and B;
Liver histology in grading and staging of chronic liver disease; histochemical tests for improvement of diagnosis of chronic liver damage;
Etiopathogenesis of primary biliary cirrhosis;
Portal blood flow for diagnostic of portal hypertension;
 Pathogenesis of minimal hepatic encephalopathy;
Atnaujinta 2014-10-31
Straipsnis parodytas: 10309 kartų(kartus)
 

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